I've been using this primarily for my Mother who has moderate symptoms of Dementia, Metablolic Syndrome, high blood pressure and bladder control issues. I feel it has helped her be able to go to bed and not wake up so frequently for bladder relief. She does seem calmer in the waking hours. It's too soon to tell how it will affect her conditions long term, but I feel it has been beneficial short-term. I must comment also on the aroma and taste of the tinctures as I have used many in the past. They are exquisite. They are very easy to use and do not repel a person as to their taste or odor. I literally feel as though we found a pot of gold and in the end, this may be an understatement. Thank you Alex for a wonderful product and the Christmas discount that helped me greatly in getting a variety to try in the coming months. I feel we are hooked now into something beneficial, very much so. Peace and blessings!